1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone
1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone
CAS: 172739-45-6
Molecular Formula: C11H13ClO3
1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone - Names and Identifiers
1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone - Physico-chemical Properties
| Molecular Formula | C11H13ClO3 |
| Molar Mass | 228.67 |
| Density | 1.217±0.06 g/cm3(Predicted) |
| Melting Point | 73-74° |
| Boling Point | 388.2±27.0 °C(Predicted) |
| pKa | 9.77±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD04126369 |
1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone - Risk and Safety
| Hazard Class | IRRITANT |
1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone - Introduction
1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone is an organic compound whose chemical formula is C12H13ClO3. The following is an introduction to several aspects of it:
Nature:
-Appearance: White or off-white crystalline solid
-Solubility: Soluble in some organic solvents such as ethanol and dichloromethane, insoluble in water
-melting point: about 90-95 ℃
Use:
1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone has some applications in pharmaceutical and organic synthesis:
-It is widely used as an intermediate in organic synthesis for the synthesis of biologically active compounds
-It can also be used as an additive in synthetic dyes, optical materials and coatings
Preparation Method:
There are many ways to prepare 1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone. Here is a typical method:
-First, introduce a hydroxyl group on the benzene ring, and 4-hydroxybenzonitrile can be obtained through hydroxylation.
-Then, it is reacted with chloropropanol to obtain the target compound 1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone.
Safety Information:
- 1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone is a chemical that should be used with personal protective measures to avoid contact with skin, eyes and mouth.
-During operation, it should be carried out in a well-ventilated place to prevent inhalation of its vapor.
-When storing and using, keep it away from fire and oxidant to avoid the risk of fire and explosion.
-If you come into contact with this compound, rinse immediately with plenty of water and seek medical advice.
Please note that the information provided here is for reference only. If you have specific needs or more details, it is recommended to consult relevant experts or consult accurate chemical literature.
Nature:
-Appearance: White or off-white crystalline solid
-Solubility: Soluble in some organic solvents such as ethanol and dichloromethane, insoluble in water
-melting point: about 90-95 ℃
Use:
1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone has some applications in pharmaceutical and organic synthesis:
-It is widely used as an intermediate in organic synthesis for the synthesis of biologically active compounds
-It can also be used as an additive in synthetic dyes, optical materials and coatings
Preparation Method:
There are many ways to prepare 1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone. Here is a typical method:
-First, introduce a hydroxyl group on the benzene ring, and 4-hydroxybenzonitrile can be obtained through hydroxylation.
-Then, it is reacted with chloropropanol to obtain the target compound 1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone.
Safety Information:
- 1-[4-(3-Chloropropoxy)-2-hydroxyphenyl]-1-ethanone is a chemical that should be used with personal protective measures to avoid contact with skin, eyes and mouth.
-During operation, it should be carried out in a well-ventilated place to prevent inhalation of its vapor.
-When storing and using, keep it away from fire and oxidant to avoid the risk of fire and explosion.
-If you come into contact with this compound, rinse immediately with plenty of water and seek medical advice.
Please note that the information provided here is for reference only. If you have specific needs or more details, it is recommended to consult relevant experts or consult accurate chemical literature.
Last Update：2024-04-10 22:29:15
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